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Fig. S5
Examination of the Expression of the UPR mediator BiP in Transgenic Fish Overexpressing MAN1A1 and MAN1C1 by IHC Staining. IHC was performed on liver sections from different fish ages (3M to 11M). The BiP signal present in MAN1A1 overexpressing transgenic fish starts at 3M but is little in MAN1C1 transgenic fish, and almost undetectable in EGFP-mCherry control fish. These images were taken at 400X magnification and the scale shown is 30 μm. N=5 each stage per transgenic line.
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