ZFIN Image: Lai et al., 2017, Fig. 1

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Fig. 1

Under-maturation of oogenesis was shown in topiramate-treated female fish. Developmental status of oocyte in maternal fish was determined by Hematoxylin and eosin (H & E) staining. (A) Generally, the ovary was filled with mature oocytes in control fish in a high percentage; (B–F) however, a decreased percentage of mature oocytes was detected in different topiramate-treated female fish. Identification of the maturation stage was based on morphologies (I, primary growth stage; II, early cortical alveolus stage; II *, mid-cortical alveolus stage III, vitellogesis stage; IV, mature oocyte); (G) statistical analysis of oogenesis stages. Columns represent the number of cells at the four stages as percentages of the total counted (averages ± SD; *** p < 0.005; control n = 8; topiramate-treated n = 7).

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Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Int. J. Mol. Sci.