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Fig. 5
Apical alterations in zebrafish thyrocytes caused by propylthiouracil exposure. At concentrations ≥10 mg/L, cytoplasmic inclusions were evident (A). At concentrations ≥2.5 mg/L, numerous apical vesicles were seen protruding into the follicular lumen (B). Bleb-like structures indicate endo- or exocytotic processes at concentrations ≥10 mg/L (B, C). Moderate proliferation of microvilli can be observed at concentrations ≥10 mg/L (▸; B). Magnifications: A: 12,500×; B: 8,000×; C: 20,000×.
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