ZFIN Image: Helmprobst et al., 2015, Fig. 6

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Figure Caption

Fig. 6

Dense projections link synaptic vesicles to the presynaptic membrane. Shown are tomograms of dense projections in 4-dpf (A,D) and 8-dpf (G) zebrafish. They were segmented (B,E,H) and rendered into 3D models (C,F,I). Light green, presynaptic membrane; dark green, dense projection; white, synaptic vesicles; red, docked vesicles. All segmentations and 3D models show only the vesicles directly connected to dense projections. A-C and D-F: Typical dense projections in 4-dpf larvae. G-I: Dense projections found in 8-dpf larvae. J: Same tomogram as in D but showing all dense projections found. For a better overview, all vesicles are shown as transparent (J). A magenta/green version of this figure is available as Supporting Information Figure 2. Scale bars = 50 nm in in A,B,D-H,J; 100 nm in C,I.

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ J. Comp. Neurol.