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Fig. S3

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ZDB-IMAGE-150422-55
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Figures for Olena et al., 2015
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Fig. S3

Knockdown of snx5 and overexpression of miR-216a result in vascular patterning defects. Tg(flk1:eGFP) embryos were injected at the 1-cell stage with dye control, snx5MOs, or miR-216a. Embryos were grown in egg water and vascular development was monitored. Intersegmental vessels were missing in the trunks of snx5MOs - and miR-216a-injected larvae at 4dpf, but not from dye control-injected larvae. Left column contains representative images, and right column shows vessels outlined with dotted white lines in order to highlight the absence of some vessels.

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Reprinted from Developmental Biology, 400(1), Olena, A.F., Rao, M.B., Thatcher, E.J., Wu, S.Y., Patton, J.G., miR-216a regulates snx5, a novel notch signaling pathway component, during zebrafish retinal development, 72-81, Copyright (2015) with permission from Elsevier. Full text @ Dev. Biol.