IMAGE

Fig. 2

ID

ZDB-IMAGE-150413-2

Genes

Publication

Banerjee et al., 2015 - Zebrafish foxc1a drives appendage-specific neural circuit development

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Figures for Banerjee et al., 2015

Image

Figure Caption

Fig. 2

The p162 mutant phenotype is caused by a nonsense mutation in the foxc1a gene. (A,B) The G to A nucleotide mutation converts tryptophan at position 118 into a premature stop codon. (C) Conceptual translation of the foxc1a^p162 predicts a 117 amino acid protein truncated within the forkhead (FH) domain. (D) Injection of wild-type foxc1a mRNA restores axon guidance in foxc1a mutants. (E) Quantification of the mRNA rescue. Numbers on top of individual bars indicate the number of hemisegments and embryos (brackets) analyzed. For all genotypes, only the first six anterior segments were analyzed. Scale bar: 10µm in D.

Figure Data

Expression / Labeling details

Phenotype details

Acknowledgments

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