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Fig. 5
ROS overproduction by the LSC inhibitors.
(A) LSC inhibitors (10 µM) significantly inhibited the in vitro proliferation of ALDH+ cells 24 h after treatment (n = 3), **P<0.01. (B) Typical images showing ROS production in ALDH+ cells. LSC inhibitors (10 µM) significantly induced in vitro ROS production in cells treated for 24 h. Blue, nucleus; red, ROS. Scale bar: 50 µm. (C) Quantitative analysis of ROS in the cells (n = 4), **P<0.01.
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