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Fig. 1 Effect of inhibition of the FGF-receptor on normal development. Live embryos at 48 hpf. (A) Normal embryo, arrows indicate otic vesicle (1), somite 1 (2), and somite 17 (3). (B) Extreme phenotype resulting from expression of the dominant negative FGF-receptor: all structures posterior to the otic vesicle are missing. (C) Homozygous no tail mutant, which lacks only the body axis posterior to somite 17-19, and the notochord.
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