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Fig. 3
Knock-down of tbx2a affects pharyngeal arches.
(A, B) tbx2a knock-down results in a loss of GFP-positive pharyngeal arches visualized on a background of ET33-1B transgenics. Alcian Blue-stained cartilages are present in the pharyngeal arches of tp53 morphant (C), but not in the tbx2a/tp53 morphants (D). At 24 hpf, dlx2a-positive streams of migratory NCCs (C) develop normally in the morphant (D) even after injection of a high dose of MO (E). At 48hpf, the patterning of posterior arches is affected (arrows and asterisks in F, G).
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