IMAGE

Fig. S3

ID
ZDB-IMAGE-130118-9
Source
Figures for Freitas et al., 2012
Image
Figure Caption

Fig. S3 Fin alterations are both hormone and hoxd13a dependent. A, Similar and1 expression domains were observed in wild type or hoxa4a-GR injected fins, either in the presence or the absence of the hormone (arrows). In fins injected with hoxd13a-GR, and1 is only downregulated in the presence of Dex (arrowhead). B, Expression of hoxa13b and cyclin d1 is not affected in hoxa4a-GR injected or wt fins in the presence of Dex (upper and middle panels, arrows). Distal expansion of hoxa13b and cyclin d1 domains is observed in hoxd13a-GR overexpressing fins (lower panel, arrowheads).

Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image.

Reprinted from Developmental Cell, 23(6), Freitas, R., Gómez-Marín, C., Wilson, J.M., Casares, F., and Gómez-Skarmeta, J.L., Hoxd13 contribution to the evolution of vertebrate appendages, 1219-1229, Copyright (2012) with permission from Elsevier. Full text @ Dev. Cell