ZFIN Image: Asai et al., 2006, Fig. 5

Image

Figure Caption

Fig. 5

The expression of fgf8 and sef genes in WT and atrophin2 knockdown embryos. (A) In a control embryo at 24 hpf, fgf8 transcripts are detected in the telencephalon, optic stalk, isthmus, otic vesicle, developing somites, and tail bud. (B) fgf8 is expressed more broadly in an atrophin2 knockdown embryo. (C) A 26-somite control embryo treated with sef probe displays prominent labeling of the optic cup and otic vesicle. (D) An atrophin2 knockdown embryo shows a similar pattern of labeling but more extensive expression than in control fish. (E) Quantitative PCR analysis confirms the increased expression of messages for fgf8, sef, and sprouty4 in atrophin2 knockdown animals; significance values were obtained with Student′s one-tailed t test. Control animals were injected with water. The error bars indicate standard deviations. (Scale bar: 100 μm.)

Figure Data

Expression / Labeling details

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Proc. Natl. Acad. Sci. USA