IMAGE

Fig. 6

ID
ZDB-IMAGE-110804-14
Genes
Antibodies
Source
Figures for Kapsimali et al., 2011
Image
Figure Caption

Fig. 6

Delta and ascl1a activity are necessary for intact taste bud organ formation. Genotypes are indicated in the top right-hand corner, embryonic stage and scale bar are in the bottom left-hand corner and marker expression is in the bottom right-hand corner. (A,B) Anterior is towards the top. Ventral confocal projections of the first branchial arch showing dlb overexpression in mib–/– (B) compared with the wild-type sibling (A). (C-H,M,N) Anterior is towards the left. Ventral views. Asterisks in F-H indicate taste buds in the lips. 5HT+ and ascl1a-expressing cells are increased in number (D,H) and Calb2b+ and miR-200a-expressing cells reduced in number (D,F) in mib–/– compared with the wild type (C,G and C,E, respectively). By contrast, 5HT+ (green) cells are absent and Calb2b+ (red) cells disorganized in the ascl1a–/– pharynx (N) compared with the wild type (M). (I-L) Transverse sections of wild-type (I,K) and mib–/– siblings (J,L) labeled with the pea3 probe. Arrows indicate pea3 expression in the pharyngeal arch epithelium (I,J, hyoid; K,L, b4). Scale bars: 15 μm. b1-b5, branchial arches 1-5; h, hyoid arch; m, mandibular arch; ov, otic vesicle; hy, hypothalamus.

Figure Data
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Development