IMAGE

Fig. 4

ID
ZDB-IMAGE-101208-27
Genes
Source
Figures for Schneider et al., 2010
Image
Figure Caption

Fig. 4 Asymmetric charon expression around the KV is dependent on Nkd1 and cilia function. Expression of charon in wt (A), CtrlMODFC (B), and Nkd1MODFC (C) embryos. Expression of charon in InvsMO (D), SeaMO (E), and Ift88MO (F) injected embryos. Dashed line represents embryonic midline. (G) Graph of percent of embryos displaying left-sided (white bar), no bias (shaded bar) or right-sided biased (black bar) charon expression around KV. (n) notes the sample size for each injection set. ** = p > 0.01 compared to wt using Fisher′s exact test. Nkd1MODFC p-value = 3.07 × 10- 16; Nkd1MODFC+ nkd1 RNA p-value = 0.01, SeaMO p-value = 2.3 × 10- 11; Ift88MO p-value = 3.5 × 10- 9; InvsMO p-value = 2.11 × 10- 8.

Figure Data
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image.

Reprinted from Developmental Biology, 348(1), Schneider, I., Schneider, P.N., Derry, S.W., Lin, S., Barton, L.J., Westfall, T., and Slusarski, D.C., Zebrafish Nkd1 promotes Dvl degradation and is required for left-right patterning, 22-33, Copyright (2010) with permission from Elsevier. Full text @ Dev. Biol.