ZFIN Image: Winata et al., 2009, Fig. S5

Image

Figure Caption

Fig. S5 Rescue of syu^t4 phenotype by purmorphamine (PA). (A–C) Phenotype of control (A,D,G), untreated homozygous syu^t4 (B,E,H), and PA-treated homozygous syu^t4 larvae (C,F,I) at 24 hpf (A–C) and 54 hpf (D–F). (G–I) show EGFP expression in Et(krt4:EGFP)^sq33-2. Note the presence of an anteriorly shifted swimbladder bud in rescued larvae and absence in untreated homozygous mutants. (J–O) Phenotype at 72 hpf, note the presence of a larger swimbladder bud in rescued homozygous syu^t4 compared to the untreated one. Swimbladder bud in rescued larvae is also located one somite more anteriorly compared to that in control. Numbers represent somites. Sb, swimbladder. Scale bars: 250 μm.

Figure Data

Phenotype details

Acknowledgments

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Reprinted from Developmental Biology, 331(2), Winata, C.L., Korzh, S., Kondrychyn, I., Zheng, W., Korzh, V., and Gong, Z., Development of zebrafish swimbladder: the requirement of Hedgehog signaling in specification and organization of the three tissue layers, 222-236, Copyright (2009) with permission from Elsevier. Full text @ Dev. Biol.