Image
|
Figure Caption
Fig. 5 NMR Analysis of Potential Intramolecular Interactions of β-Catenin
NMR studies suggest highly dynamic interactions between the C-terminal tail and the β-catenin N-R12 fragment 15N-TROSY spectra of the 15N-labeled β-catenin(687–781) alone (green) and with unlabeled β-catenine(1–686) (red). Poor dispersion of the resonance indicates that β-catenin(687–781) is unstructured in the absence or presence of β-catenine(1–686). Some minor chemical shift perturbations, as indicated by the arrows, suggest that β-catenin(687–781) may interact with β-catenine(1–686) in a highly dynamic manner.
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and
ZFIN has permission only to display this image to its users.
Additional permissions should be obtained from the applicable author or publisher of the image.
Reprinted from Structure (London, England : 1993), 16(3), Xing, Y., Takemaru, K., Liu, J., Berndt, J.D., Zheng, J.J., Moon, R.T., and Xu, W., Crystal Structure of a Full-Length beta-Catenin, 478-487, Copyright (2008) with permission from Elsevier. Full text @ Structure