Gene

opn1sw1

ID

ZDB-GENE-991109-25

Name

opsin 1 (cone pigments), short-wave-sensitive 1

Symbol

opn1sw1 Nomenclature History

Previous Names

SWS1 (1)
uvops
zfuv

Type

protein_coding_gene

Location

Chr: 4 Mapping Details/Browsers

Description

Predicted to have G protein-coupled photoreceptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway; cellular response to light stimulus; and phototransduction. Predicted to localize to integral component of plasma membrane and photoreceptor outer segment. Human ortholog(s) of this gene implicated in blue color blindness. Is expressed in several structures, including digestive system; endocrine system; heart; photoreceptor cell; and visual system. Orthologous to human OPN1SW (opsin 1, short wave sensitive).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

77 figures from 55 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

MGC:73050 (2 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 1 Figure from Yoshimatsu et al., 2014
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With opn1sw1 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
blue color blindness	Alliance	Colorblindness, tritan	190900

Associated With opn1sw1 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Binding_site	IPR027430	Visual pigments (opsins) retinal binding site
Domain	IPR017452	GPCR, rhodopsin-like, 7TM
Family	IPR000276	G protein-coupled receptor, rhodopsin-like
Family	IPR001521	Opsin, blue sensitive
Family	IPR001760	Opsin