Gene

tmod4

ID
ZDB-GENE-991019-9
Name
tropomodulin 4 (muscle)
Symbol
tmod4 Nomenclature History
Previous Names
  • Sk-Tmod (1)
  • sktmod (1)
  • fa12b03
  • skeletal tropomodulin (1)
  • wu:fa12b03
Type
protein_coding_gene
Location
Chr: 16 Mapping Details/Browsers
Description
Predicted to enable tropomyosin binding activity. Acts upstream of or within skeletal myofibril assembly. Predicted to be located in cytoplasm. Predicted to be active in striated muscle thin filament. Is expressed in head muscle and myotome. Orthologous to human TMOD4 (tropomodulin 4).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
2 figures from Berger et al., 2014
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
7 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Allele Type Localization Consequence Mutagen Supplier
hu3476Allele with one point mutationUnknownMissenseENU
hu3530Allele with one point mutationUnknownPremature StopENU
pc20Allele with one point mutationExon 5Premature Stopnot specified
sa18609Allele with one point mutationUnknownPremature StopENU
sa22870Allele with one point mutationUnknownPremature StopENU
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Sequence Targeting Reagents
Targeting Reagent Created Alleles Citations
MO1-tmod4N/ABerger et al., 2014
1 - 1 of 1
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Human Disease
Associated With tmod4 Human Ortholog
No data available
Associated With tmod4 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR004934 Tropomodulin
Homologous_superfamily IPR032675 Leucine-rich repeat domain superfamily
1 - 2 of 2
Domain Details Per Protein
Protein Additional Resources Length Leucine-rich repeat domain superfamily Tropomodulin
UniProtKB:Q9PUQ6 InterPro 343
1 - 1 of 1
Transcripts
Genome Browsers
Genome Build: GRCz11Chromosome: 16
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA tmod4-201 (1) Ensembl 1,717 nt
mRNA tmod4-202 (1) Ensembl 2,087 nt
1 - 2 of 2
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-tmod4 polyclonal IgG Rabbit
  • WB
Proteintech
2
1 - 1 of 1
Plasmids
No data available
Constructs
No data available
Marker Relationships
Relationship Marker Type Marker Accession Numbers Citations
Contained inBACCH211-203D17ZFIN Curated Data
EncodesESTfa12b03
EncodescDNAMGC:77859ZFIN Curated Data
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Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Species Symbol Chromosome Accession # Evidence
HumanTMOD41
Conserved genome location (synteny) (1)
Amino acid sequence comparison (1)
MouseTmod43
Conserved genome location (synteny) (1)
Amino acid sequence comparison (1)
Citations
1 - 9 of 9
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