Gene

pparda

ID
ZDB-GENE-990415-212
Name
peroxisome proliferator-activated receptor delta a
Symbol
pparda Nomenclature History
Previous Names
  • FAAR (1)
  • PPAR[b]
  • pparb
  • NR1C2-A (1)
  • nr1c2a (1)
  • NUC1 (1)
  • PPARbeta-A (1)
  • wu:fb60c11
Type
protein_coding_gene
Location
Chr: 22 Mapping Details/Browsers
Description
Exhibits sequence-specific DNA binding activity. Involved in neural crest cell development and response to activity. Localizes to chromatin. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Is expressed in several structures, including intestine; liver; ovary; pectoral fin; and pharyngeal arch. Orthologous to human PPARD (peroxisome proliferator activated receptor delta).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
12 figures from 6 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With pparda Human Ortholog
No data available
Associated With pparda Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000536 Nuclear hormone receptor, ligand-binding domain
Domain IPR001628 Zinc finger, nuclear hormone receptor-type
Family IPR001723 Nuclear hormone receptor
Family IPR003074 Peroxisome proliferator-activated receptor
Family IPR003075 Peroxisome proliferator-activated receptor, beta
Homologous_superfamily IPR013088 Zinc finger, NHR/GATA-type
Homologous_superfamily IPR035500 Nuclear hormone receptor-like domain superfamily
Domain Details Per Protein
Protein Length Nuclear hormone receptor Nuclear hormone receptor, ligand-binding domain Nuclear hormone receptor-like domain superfamily Peroxisome proliferator-activated receptor Peroxisome proliferator-activated receptor, beta Zinc finger, NHR/GATA-type Zinc finger, nuclear hormone receptor-type
UniProtKB:F8W3D2 496
UniProtKB:F1QJT0 472
UniProtKB:O42549 31
UniProtKB:Q90Z67 329
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations