Gene

ccne1

ID
ZDB-GENE-980526-168
Name
cyclin E1
Symbol
ccne1 Nomenclature History
Previous Names
  • ccne (1)
  • cyce (1)
  • fa18e07
  • wu:fa18e07 (1)
Type
protein_coding_gene
Location
Chr: 7 Mapping Details/Browsers
Description
Exhibits kinase activity. Predicted to be involved in G1/S transition of mitotic cell cycle and regulation of cyclin-dependent protein serine/threonine kinase activity. Predicted to localize to several cellular components, including centrosome; cyclin E1-CDK2 complex; and nucleus. Is expressed in anterior axial hypoblast; intestine; nervous system; notochord; and polster. Human ortholog(s) of this gene implicated in breast adenocarcinoma. Orthologous to human CCNE1 (cyclin E1).
Genome Resources
Note
None
Expression
All Expression Data
21 figures from 14 publications
Cross-Species Comparison
High Throughput Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ccne1 Human Ortholog
No data available
Associated With ccne1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR004367 Cyclin, C-terminal domain
Domain IPR006671 Cyclin, N-terminal
Domain IPR013763 Cyclin-like
Family IPR028858 Cyclin E
Family IPR039361 Cyclin
Homologous_superfamily IPR036915 Cyclin-like superfamily
Domain Details Per Protein
Protein Length Cyclin Cyclin, C-terminal domain Cyclin E Cyclin-like Cyclin-like superfamily Cyclin, N-terminal
UniProtKB:A0A2R8Q3B0 410
UniProtKB:A0A0R4IZF8 410
UniProtKB:B2GQF9 410
UniProtKB:P47794 410
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations