Gene

grxcr1a

ID
ZDB-GENE-160113-42
Name
glutaredoxin and cysteine rich domain containing 1 a
Symbol
grxcr1a Nomenclature History
Previous Names
  • si:dkey-109l4.6 (1)
Type
protein_coding_gene
Location
Chr: 14 Mapping Details/Browsers
Description
Predicted to have electron transfer activity and protein disulfide oxidoreductase activity. Involved in auditory receptor cell morphogenesis. Is expressed in hair cell anterior macula. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 25. Orthologous to human GRXCR1 (glutaredoxin and cysteine rich domain containing 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
2 figures from Blanco-Sánchez et al., 2018
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
4 figures from Blanco-Sánchez et al., 2018
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With grxcr1a Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
autosomal recessive nonsyndromic deafness 25 Alliance Deafness, autosomal recessive 25 613285
Associated With grxcr1a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR002109 Glutaredoxin
Family IPR042797 Glutaredoxin domain-containing cysteine-rich protein 1
Homologous_superfamily IPR036249 Thioredoxin-like superfamily
Domain Details Per Protein
Protein Length Glutaredoxin Glutaredoxin domain-containing cysteine-rich protein 1 Thioredoxin-like superfamily
UniProtKB:A0A140LFN7 295
UniProtKB:A0A286YA02 295
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-grxcr1a polyclonal IgG Rabbit
  • IHC
Novus Biologicals, LLC
2
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations