Gene
kynu
- ID
- ZDB-GENE-120215-204
- Name
- kynureninase
- Symbol
- kynu Nomenclature History
- Previous Names
-
- si:ch73-379f7.2
- Type
- protein_coding_gene
- Location
- Chr: 6 Mapping Details/Browsers
- Description
- Predicted to have kynureninase activity. Predicted to be involved in anthranilate metabolic process and tryptophan catabolic process to kynurenine. Predicted to localize to cytoplasm. Orthologous to human KYNU (kynureninase).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| hydroxykynureninuria | Alliance | ?Hydroxykynureninuria | 236800 |
| Vertebral, cardiac, renal, and limb defects syndrome 2 | 617661 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000192 | Aminotransferase class V domain |
| Family | IPR010111 | Kynureninase |
| Homologous_superfamily | IPR015421 | Pyridoxal phosphate-dependent transferase, major domain |
| Homologous_superfamily | IPR015422 | Pyridoxal phosphate-dependent transferase, small domain |
| Homologous_superfamily | IPR015424 | Pyridoxal phosphate-dependent transferase |
Domain Details Per Protein
| Protein | Length | Aminotransferase class V domain | Kynureninase | Pyridoxal phosphate-dependent transferase | Pyridoxal phosphate-dependent transferase, major domain | Pyridoxal phosphate-dependent transferase, small domain |
|---|---|---|---|---|---|---|
|
UniProtKB:A0A0R4IQY2
|
455 |
Interactions and Pathways
No data available
Plasmids
No data available