ZFIN is now using GRCz12tu for Genomic Data
Gene
crhr2
- ID
- ZDB-GENE-100428-1
- Name
- corticotropin releasing hormone receptor 2
- Symbol
- crhr2 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Unmapped
- Genome Assembly
- Unknown
- Annotation Status
- Unknown
- Description
- Is expressed in heart. Human ortholog(s) of this gene implicated in asthma. Orthologous to human CRHR2 (corticotropin releasing hormone receptor 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
No data available
Domain Details Per Protein
No data available
- Genome Browsers
- No data available
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers
- No data available
No data available
- Comparative Orthology
- Alliance
- Liu, M., Tang, L., Hu, C., Sun, B., Huang, Z., Chen, L. (2021) Interaction between probiotic additive and perfluorobutanesulfonate pollutant on offspring growth and health after parental exposure using zebrafish. Ecotoxicology and environmental safety. 214:112107
- Zhou, H., Chen, A., Lu, W. (2021) Corticotropin-releasing hormone reduces basal estradiol production in zebrafish follicular cells. Molecular and Cellular Endocrinology. 527:111222
- Liu, M., Song, S., Hu, C., Tang, L., Lam, J.C.W., Lam, P.K.S., Chen, L. (2020) Dietary administration of probiotic Lactobacillus rhamnosus modulates the neurological toxicities of perfluorobutanesulfonate in zebrafish. Environmental pollution (Barking, Essex : 1987). 265:114832
- Wang, L., Lin, W., Zha, Q., Guo, H., Zhang, D., Yang, L., Li, L., Li, D., Tang, R. (2020) Persistent Exposure to Environmental Levels of Microcystin-LR Disturbs Cortisol Production via Hypothalamic-Pituitary-Interrenal (HPI) Axis and Subsequently Liver Glucose Metabolism in Adult Male Zebrafish (Danio rerio). toxins. 12(5):
- Wei, P., Zhao, F., Zhang, X., Ru, S. (2020) Long-term exposure of zebrafish to bisphenol S impairs stress function of hypothalamic-pituitary-interrenal axis and causes anxiety-like behavioral responses to novelty. The Science of the total environment. 716:137092
- Zhang, Q., Yu, C., Fu, L., Gu, S., Wang, C. (2020) New Insights in the Endocrine Disrupting Effects of Three Primary Metabolites of Organophosphate Flame Retardants. Environmental science & technology. 54(7):4465-4474
- Vera-Chang, M.N., Moon, T.W., Trudeau, V.L. (2019) Cortisol disruption and transgenerational alterations in the expression of stress-related genes in zebrafish larvae following fluoxetine exposure. Toxicology and applied pharmacology. 382:114742
- Chen, L., Wang, Y., Giesy, J.P., Chen, F., Shi, T., Chen, J., Xie, P. (2018) Microcystin-LR affects the hypothalamic-pituitary-inter-renal (HPI) axis in early life stages (embryos and larvae) of zebrafish. Environmental pollution (Barking, Essex : 1987). 241:540-548
- Williams, T.A., Bergstrome, J.C., Scott, J., Bernier, N.J. (2017) CRF and urocortin 3 protect the heart from hypoxia/reoxygenation-induced apoptosis in zebrafish. American journal of physiology. Regulatory, integrative and comparative physiology. 313(2):R91-R100
- Jeffrey, J.D., Gilmour, K.M. (2016) Programming of the hypothalamic-pituitary-interrenal axis by maternal social status in zebrafish (Danio rerio). The Journal of experimental biology. 219(Pt 11):1734-43
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