Gene
fabp10b
- ID
- ZDB-GENE-100217-2
- Name
- fatty acid binding protein 10b, liver basic
- Symbol
- fabp10b Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 17 Mapping Details/Browsers
- Description
- Predicted to enable fatty acid binding activity. Predicted to be involved in fatty acid transport. Predicted to be active in cytosol and nucleus. Is expressed in several structures, including heart; integument; liver; pleuroperitoneal region; and sensory system.
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Allele | Type | Localization | Consequence | Mutagen | Supplier |
---|---|---|---|---|---|
sa43020 | Allele with one point mutation | Unknown | Splice Site | ENU |
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No data available
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
Protein | Additional Resources | Length | Calycin | Cytosolic fatty-acid binding | Intracellular lipid binding protein |
---|---|---|---|---|---|
UniProtKB:X1WFK9 | InterPro | 128 |
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Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
---|---|---|---|---|---|
mRNA |
fabp10b-201
(1)
|
Ensembl | 555 nt | ||
mRNA |
fabp10b-202
(1)
|
Ensembl | 892 nt |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
Relationship | Marker Type | Marker | Accession Numbers | Citations |
---|---|---|---|---|
Contained in | Fosmid | ZFOS-1714F5 | ||
interacts with | Promoter | fabp10b_promoter | Laprairie et al., 2017 |
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Type | Accession # | Sequence | Length (nt/aa) | Analysis |
---|---|---|---|---|
RNA | RefSeq:NM_001386838 (1) | 581 nt | ||
Genomic | GenBank:FP017231 (2) | 35910 nt | ||
Polypeptide | UniProtKB:X1WFK9 (1) | 128 aa |
No data available
- Shi, G., Cui, Q., Wang, J., Guo, H., Pan, Y., Sheng, N., Guo, Y., Dai, J. (2019) Chronic exposure to 6:2 chlorinated polyfluorinated ether sulfonate acid (F-53B) induced hepatotoxic effects in adult zebrafish and disrupted the PPAR signaling pathway in their offspring. Environmental pollution (Barking, Essex : 1987). 249:550-559
- Laprairie, R.B., Denovan-Wright, E.M., Wright, J.M. (2017) Differential regulation of the duplicated fabp7, fabp10 and fabp11 genes of zebrafish by peroxisome proliferator activated receptors. Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology. 213:81-90
- Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549
- Thirumaran, A., Wright, J.M. (2014) Fatty acid-binding protein (fabp) genes of spotted green pufferfish (Tetraodon nigroviridis): comparative genomics and spatial transcriptional regulation. Genome. 57(5):289-301
- Parmar, M.B., and Wright, J.M. (2013) Comparative genomic organization and tissue-specific transcription of the duplicated fabp7 and fabp10 genes in teleost fishes. Genome. 56(11):691-701
- Parmar, M.B., and Wright, J.M. (2013) Comparative evolutionary genomics of medaka and three-spined stickleback fabp2a and fabp2b genes with fabp2 of zebrafish. Genome. 56(1):27-37
- Parmar, M.B., Venkatachalam, A.B., and Wright, J.M. (2012) Comparative genomics and evolutionary diversification of the duplicated fabp6a and fabp6b genes in medaka and three-spined stickleback. Comparative biochemistry and physiology. Part D, Genomics & proteomics. 7(4):311-321
- Parmar, M.B., Venkatachalam, A.B., and Wright, J.M. (2012) The evolutionary relationship of the transcriptionally-active fabp11a (intron-less) and fabp11b genes of medaka with fabp11 genes of other teleost fishes. The FEBS journal. 279(13):2310-2321
- Venkatachalam, A.B., Lall, S.P., Denovan-Wright, E.M., and Wright, J.M. (2012) Tissue-specific differential induction of duplicated fatty acid-binding protein genes by the peroxisome proliferator, clofibrate, in zebrafish. BMC Evolutionary Biology. 12(1):112
- Zhang, W., Zhang, Y., Zhang, H., Wang, J., Cui, R., and Dai, J. (2012) Sex differences in transcriptional expression of FABPs in zebrafish liver after chronic perfluorononanoic acid exposure. Environmental science & technology. 46(9):5175-5182
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