Gene
cyfip2
- ID
- ZDB-GENE-080724-2
- Name
- cytoplasmic FMR1 interacting protein 2
- Symbol
- cyfip2 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 14 Mapping Details/Browsers
- Description
- Involved in activation of cysteine-type endopeptidase activity; apoptotic process; and cell morphogenesis. Acts upstream of or within retina layer formation; retinal ganglion cell axon guidance; and startle response. Predicted to be located in cytoplasm. Is expressed in central nervous system and retina. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 65. Orthologous to human CYFIP2 (cytoplasmic FMR1 interacting protein 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 19 figures from 7 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| developmental and epileptic encephalopathy 65 | Alliance | Developmental and epileptic encephalopathy 65 | 618008 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Family | IPR008081 | Cytoplasmic FMR1-interacting |
Domain Details Per Protein
| Protein | Length | Cytoplasmic FMR1-interacting |
|---|---|---|
|
UniProtKB:B3DIT1
|
1252 | |
|
UniProtKB:A5A5E1
|
1253 | |
|
UniProtKB:A0A2R8PX02
|
1254 |
| Type | Name | Length (nt) | Analysis |
|---|---|---|---|
| mRNA |
cyfip2-201
(1)
|
4023 nt | |
| mRNA |
cyfip2-202
(1)
|
5369 nt |
Interactions and Pathways
No data available
| Name | Type | Antigen Genes | Isotype | Host Organism | Assay | Source | Citations |
|---|---|---|---|---|---|---|---|
| Ab1-cyfip2 | polyclonal | IgG | Rabbit |
|
Abcam plc
|
2 |
Plasmids
No data available