Gene
nfasca
- ID
- ZDB-GENE-080229-6
- Name
- neurofascin homolog (chicken) a
- Symbol
- nfasca Nomenclature History
- Previous Names
-
- sc:d0205
- Type
- protein_coding_gene
- Location
- Chr: 11 Mapping Details/Browsers
- Description
- Predicted to enable cell-cell adhesion mediator activity. Predicted to be involved in axon guidance; brain development; and cell-cell adhesion. Predicted to be located in membrane. Predicted to be active in axon and plasma membrane. Is expressed in nervous system; pancreatic system; and trigeminal placode. Orthologous to human NFASC (neurofascin).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 8 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cssl:d205 (25 images)
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Vagionitis et al., 2022
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Neurodevelopmental disorder with central and peripheral motor dysfunction | 618356 |
1 - 1 of 1
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR003006 | Immunoglobulin/major histocompatibility complex, conserved site |
| Domain | IPR003598 | Immunoglobulin subtype 2 |
| Domain | IPR003599 | Immunoglobulin domain subtype |
| Domain | IPR003961 | Fibronectin type III |
| Domain | IPR007110 | Immunoglobulin-like domain |
1 - 5 of 11 Show all
Domain Details Per Protein
| Protein | Additional Resources | Length | Fibronectin type III | Fibronectin type III superfamily | Immunoglobulin domain subtype | Immunoglobulin I-set | Immunoglobulin-like domain | Immunoglobulin-like domain superfamily | Immunoglobulin-like fold | Immunoglobulin/major histocompatibility complex, conserved site | Immunoglobulin subtype 2 | Neurofascin, immunoglobulin-like domain | Neurofascin/L1/NrCAM, C-terminal domain |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M9PUN4 | InterPro | 1168 | |||||||||||
| UniProtKB:A0A8M9QHH2 | InterPro | 1379 | |||||||||||
| UniProtKB:C0L978 | InterPro | 1369 | |||||||||||
| UniProtKB:A0AB32TWN4 | InterPro | 1178 | |||||||||||
| UniProtKB:A0AB32TXA3 | InterPro | 1377 |
1 - 5 of 16 Show all
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
nfasca-201
(1)
|
Ensembl | 6,288 nt | ||
| mRNA |
nfasca-202
(1)
|
Ensembl | 9,923 nt | ||
| mRNA |
nfasca-203
(1)
|
Ensembl | 4,007 nt | ||
| mRNA |
nfasca-204
(1)
|
Ensembl | 4,110 nt | ||
| mRNA |
nfasca-205
(1)
|
Ensembl | 4,066 nt |
1 - 5 of 5
Interactions and Pathways
No data available
Plasmids
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | DKEY-158N23 | ZFIN Curated Data | |
| Encodes | cDNA | cssl:d205 | Bushell et al., 2007 |
1 - 2 of 2
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