Gene

col15a1b

ID

ZDB-GENE-070912-689

Name

collagen, type XV, alpha 1b

Symbol

col15a1b Nomenclature History

Previous Names

cb491 (1)
col15a1
mz98 (1)
sb:cb491
si:dkeyp-93c5.1
wu:fb50f05
wu:fc22d09

Type

protein_coding_gene

Location

Chr: 2 Mapping Details/Browsers

Description

Predicted to be an extracellular matrix structural constituent. Acts upstream of or within eye development and regulation of motor neuron axon guidance. Predicted to be part of collagen trimer. Predicted to be active in extracellular matrix and extracellular space. Is expressed in several structures, including aortic arch; digestive system; nervous system; neural plate; and neural tube. Orthologous to human COL15A1 (collagen type XV alpha 1 chain).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

29 figures from 11 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

cb491 (27 images)
IMAGE:7158238 (13 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 9 figures from 2 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With col15a1b Human Ortholog

No data available

Associated With col15a1b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR001791	Laminin G domain
Domain	IPR010515	Collagenase NC10/endostatin
Domain	IPR045463	Collagen type XV/XVIII, trimerization domain
Homologous_superfamily	IPR013320	Concanavalin A-like lectin/glucanase domain superfamily
Homologous_superfamily	IPR016186	C-type lectin-like/link domain superfamily
Homologous_superfamily	IPR016187	C-type lectin fold
Repeat	IPR008160	Collagen triple helix repeat

Domain Details Per Protein

Protein	Length	Collagenase NC10/endostatin	Collagen triple helix repeat	Collagen type XV/XVIII, trimerization domain	Concanavalin A-like lectin/glucanase domain superfamily	C-type lectin fold	C-type lectin-like/link domain superfamily	Laminin G domain
UniProtKB:A0A0A1I9R6 InterPro	1245
UniProtKB:A0A2R8QFF2 InterPro	1170
UniProtKB:D3GN36 InterPro	1169
UniProtKB:C7SEQ6 InterPro	236
UniProtKB:F1QM25 InterPro	1245
UniProtKB:F1QT12 InterPro	1170