ZFIN is now using GRCz12tu for Genomic Data
Gene
col15a1b
- ID
- ZDB-GENE-070912-689
- Name
- collagen, type XV, alpha 1b
- Symbol
- col15a1b Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 2 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to be an extracellular matrix structural constituent conferring tensile strength. Acts upstream of or within eye development; motor neuron axon guidance; and regulation of motor neuron axon guidance. Predicted to be active in extracellular matrix. Is expressed in several structures, including aortic arch; digestive system; nervous system; neural plate; and neural tube. Orthologous to human COL15A1 (collagen type XV alpha 1 chain).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 34 figures from 16 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb491 (27 images)
- IMAGE:7158238 (13 images)
Wild Type Expression Summary
- All Phenotype Data
- 12 figures from 3 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR010515 | Collagenase NC10/endostatin |
| Domain | IPR045463 | Collagen type XV/XVIII, trimerization domain |
| Domain | IPR048287 | Thrombospondin-like, N-terminal domain |
| Family | IPR050149 | Collagen superfamily |
| Homologous_superfamily | IPR013320 | Concanavalin A-like lectin/glucanase domain superfamily |
| Homologous_superfamily | IPR016186 | C-type lectin-like/link domain superfamily |
| Homologous_superfamily | IPR016187 | C-type lectin fold |
| Repeat | IPR008160 | Collagen triple helix repeat |
Domain Details Per Protein
| Protein | Additional Resources | Length | Collagenase NC10/endostatin | Collagen superfamily | Collagen triple helix repeat | Collagen type XV/XVIII, trimerization domain | Concanavalin A-like lectin/glucanase domain superfamily | C-type lectin fold | C-type lectin-like/link domain superfamily | Thrombospondin-like, N-terminal domain |
|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:D3GN36 | InterPro | 1169 | ||||||||
| UniProtKB:A0A8M2BIM9 | InterPro | 1259 | ||||||||
| UniProtKB:A0A8M3APP4 | InterPro | 1315 | ||||||||
| UniProtKB:A0A8M2BII4 | InterPro | 1301 | ||||||||
| UniProtKB:A0A8M3B7P8 | InterPro | 1303 | ||||||||
| UniProtKB:A0A8M6Z1E7 | InterPro | 1245 | ||||||||
| UniProtKB:A0AC58GW99 | InterPro | 1289 | ||||||||
| UniProtKB:A0AC58GWA4 | InterPro | 1247 | ||||||||
| UniProtKB:A0AC58GWB5 | InterPro | 1233 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
col15a1b-201
(1)
|
Ensembl | 3,738 nt | ||
| mRNA |
col15a1b-202
(1)
|
Ensembl | 4,560 nt | ||
| mRNA |
col15a1b-203
(1)
|
Ensembl | 3,513 nt |
Interactions and Pathways
No data available
| Name | Type | Antigen Genes | Isotype | Host Organism | Assay | Source | Citations |
|---|---|---|---|---|---|---|---|
| Ab2-col15a1b | polyclonal | Guinea pig |
|
3 | |||
| Ab1-col15a1b | polyclonal | Rabbit |
|
1 |
Plasmids
No data available
- Genome Browsers