Gene

nr4a3

ID
ZDB-GENE-070824-4
Name
nuclear receptor subfamily 4, group A, member 3
Symbol
nr4a3 Nomenclature History
Previous Names
  • NOR1 (1)
Type
protein_coding_gene
Location
Chr: 16 Mapping Details/Browsers
Description
Predicted to have RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and glucocorticoid receptor binding activity. Involved in neutrophil homeostasis. Predicted to localize to nucleus and transcription factor complex. Human ortholog(s) of this gene implicated in extraskeletal myxoid chondrosarcoma. Is expressed in basal plate midbrain region; brain; neurons; and spinal cord. Orthologous to human NR4A3 (nuclear receptor subfamily 4 group A member 3).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
8 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Prince et al., 2017
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With nr4a3 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
extraskeletal myxoid chondrosarcoma Alliance Chondrosarcoma, extraskeletal myxoid 612237
Associated With nr4a3 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000536 Nuclear hormone receptor, ligand-binding domain
Domain IPR001628 Zinc finger, nuclear hormone receptor-type
Family IPR001723 Nuclear hormone receptor
Family IPR003070 Orphan nuclear receptor
Family IPR003073 Orphan nuclear receptor, NURR type
Homologous_superfamily IPR013088 Zinc finger, NHR/GATA-type
Homologous_superfamily IPR035500 Nuclear hormone receptor-like domain superfamily
Domain Details Per Protein
Protein Length Nuclear hormone receptor Nuclear hormone receptor, ligand-binding domain Nuclear hormone receptor-like domain superfamily Orphan nuclear receptor Orphan nuclear receptor, NURR type Zinc finger, NHR/GATA-type Zinc finger, nuclear hormone receptor-type
UniProtKB:Q1L695 594
UniProtKB:E9QI47 186
UniProtKB:F1R8N1 594
UniProtKB:A0A0R4IMQ4 593
UniProtKB:I6LBI4 593
Transcripts
Genome Browsers
Interactions and Pathways
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations