Gene
coq2
- ID
- ZDB-GENE-070410-84
- Name
- coenzyme Q2 4-hydroxybenzoate polyprenyltransferase
- Symbol
- coq2 Nomenclature History
- Previous Names
-
- zgc:162600
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Description
- Predicted to have 4-hydroxybenzoate decaprenyltransferase activity. Predicted to be involved in ubiquinone biosynthetic process. Predicted to localize to integral component of mitochondrial inner membrane. Human ortholog(s) of this gene implicated in primary coenzyme Q10 deficiency 1. Orthologous to human COQ2 (coenzyme Q2, polyprenyltransferase).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Mugoni et al., 2013
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| primary coenzyme Q10 deficiency 1 | Alliance | Coenzyme Q10 deficiency, primary, 1 | 607426 |
| {Multiple system atrophy, susceptibility to} | 146500 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | 4-hydroxybenzoate polyprenyltransferase-like | Prenyltransferase | UbiA prenyltransferase conserved site | UbiA prenyltransferase family | UbiA prenyltransferase superfamily |
|---|---|---|---|---|---|---|
|
UniProtKB:A3KNW5
|
378 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available