Gene
dmc1
- ID
- ZDB-GENE-060331-93
- Name
- DNA meiotic recombinase 1
- Symbol
- dmc1 Nomenclature History
- Previous Names
-
- zgc:136628
- Type
- protein_coding_gene
- Location
- Chr: 12 Mapping Details/Browsers
- Description
- Predicted to enable DNA binding activity and catalytic activity, acting on DNA. Predicted to be involved in DNA recombination and chromosome organization involved in meiotic cell cycle. Predicted to act upstream of or within DNA repair and meiotic cell cycle. Predicted to be located in nucleus. Predicted to be active in condensed nuclear chromosome. Is expressed in ovary; spermatocyte; and testis. Orthologous to human DMC1 (DNA meiotic recombinase 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 8 figures from 5 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
| Targeting Reagent | Created Alleles | Citations |
|---|---|---|
| CRISPR1-dmc1 | Zebrafish Nomenclature Committee |
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Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR003593 | AAA+ ATPase domain |
| Domain | IPR013632 | DNA recombination and repair protein Rad51-like, C-terminal |
| Domain | IPR020587 | DNA recombination and repair protein RecA, monomer-monomer interface |
| Domain | IPR020588 | DNA recombination and repair protein RecA-like, ATP-binding domain |
| Family | IPR011940 | Meiotic recombination protein Dmc1 |
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Domain Details Per Protein
| Protein | Additional Resources | Length | AAA+ ATPase domain | DNA recombination and repair protein Rad51-like, C-terminal | DNA recombination and repair protein, RecA-like | DNA recombination and repair protein RecA-like, ATP-binding domain | DNA recombination and repair protein RecA, monomer-monomer interface | DNA repair Rad51/transcription factor NusA, alpha-helical | Meiotic recombination protein Dmc1 | P-loop containing nucleoside triphosphate hydrolase |
|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:Q50LF4 | InterPro | 342 |
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Interactions and Pathways
No data available
Plasmids
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | DKEY-16I5 | ZFIN Curated Data | |
| Encodes | cDNA | MGC:136628 | ZFIN Curated Data | |
| Encodes | cDNA | MGC:194181 | ZFIN Curated Data |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_001020782 (1) | 1324 nt | ||
| Genomic | GenBank:BX649366 (1) | 222310 nt | ||
| Polypeptide | UniProtKB:Q50LF4 (1) | 342 aa |