Gene

syn2b

ID
ZDB-GENE-051127-49
Name
synapsin IIb
Symbol
syn2b Nomenclature History
Previous Names
  • zgc:123199
Type
protein_coding_gene
Location
Chr: 11 Mapping Details/Browsers
Description
Predicted to enable ATP binding activity. Predicted to be involved in neurotransmitter secretion. Predicted to be located in synaptic vesicle. Predicted to be active in synaptic vesicle membrane. Is expressed in DEL; nervous system; spinal cord neural tube; and yolk syncytial layer. Human ortholog(s) of this gene implicated in schizophrenia. Orthologous to human SYN2 (synapsin II).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
7 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from See et al., 2014
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With syn2b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
schizophrenia Alliance {Schizophrenia, susceptibility to} 181500
Associated With syn2b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR019735 Synapsin, conserved site
Domain IPR020897 Synapsin, pre-ATP-grasp domain
Domain IPR020898 Synapsin, ATP-binding domain
Family IPR001359 Synapsin
Family IPR028712 Synapsin-2/3
Homologous_superfamily IPR013815 ATP-grasp fold, subdomain 1
Homologous_superfamily IPR016185 Pre-ATP-grasp domain superfamily
PTM IPR019736 Synapsin, phosphorylation site
Domain Details Per Protein
Protein Length ATP-grasp fold, subdomain 1 Pre-ATP-grasp domain superfamily Synapsin Synapsin-2/3 Synapsin, ATP-binding domain Synapsin, conserved site Synapsin, phosphorylation site Synapsin, pre-ATP-grasp domain
UniProtKB:C5NU62 695
UniProtKB:Q2YDT0 339
UniProtKB:A0A0R4IJU5 695
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations