Gene
sagb
- ID
- ZDB-GENE-050913-98
- Name
- S-antigen; retina and pineal gland (arrestin) b
- Symbol
- sagb Nomenclature History
- Previous Names
-
- sag
- Arrestin Sb (1)
- zgc:114197
- Type
- protein_coding_gene
- Location
- Chr: 15 Mapping Details/Browsers
- Description
- Predicted to enable G protein-coupled receptor binding activity. Predicted to be involved in G protein-coupled receptor internalization. Predicted to act upstream of or within signal transduction. Predicted to be active in photoreceptor inner segment and photoreceptor outer segment. Is expressed in epiphysis; eye; photoreceptor cell; retina; and retinal outer nuclear layer. Human ortholog(s) of this gene implicated in Oguchi disease-1; hereditary night blindness; retinitis pigmentosa 47; and retinitis pigmentosa 96. Orthologous to human SAG (S-antigen visual arrestin).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 5 figures from 5 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Oguchi disease-1 | Alliance | Oguchi disease-1 | 258100 |
| retinitis pigmentosa 47 | Alliance | Retinitis pigmentosa 47, autosomal recessive | 613758 |
| retinitis pigmentosa 96 | Alliance | Retinitis pigmentosa 96, autosomal dominant | 620228 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Arrestin | Arrestin, conserved site | Arrestin-like, N-terminal | Arrestin, N-terminal | Immunoglobulin E-set |
|---|---|---|---|---|---|---|---|
| UniProtKB:Q4V8R0 | InterPro | 176 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available