Gene
sagb
- ID
- ZDB-GENE-050913-98
- Name
- S-antigen; retina and pineal gland (arrestin) b
- Symbol
- sagb Nomenclature History
- Previous Names
-
- sag
- Arrestin Sb (1)
- zgc:114197
- Type
- protein_coding_gene
- Location
- Chr: 15 Mapping Details/Browsers
- Description
- Predicted to enable G protein-coupled receptor binding activity. Predicted to be involved in G protein-coupled receptor internalization and sensory perception. Predicted to act upstream of or within signal transduction. Predicted to be active in photoreceptor inner segment and photoreceptor outer segment. Is expressed in epiphysis; eye; photoreceptor cell; retina; and retinal outer nuclear layer. Human ortholog(s) of this gene implicated in Oguchi disease-1; hereditary night blindness; retinitis pigmentosa 47; and retinitis pigmentosa 96. Orthologous to human SAG (S-antigen visual arrestin).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 5 figures from 5 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Oguchi disease-1 | Alliance | Oguchi disease-1 | 258100 |
| retinitis pigmentosa 47 | Alliance | Retinitis pigmentosa 47, autosomal recessive | 613758 |
| retinitis pigmentosa 96 | Alliance | Retinitis pigmentosa 96, autosomal dominant | 620228 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Arrestin | Arrestin, conserved site | Arrestin-like, N-terminal | Arrestin, N-terminal | Immunoglobulin E-set |
|---|---|---|---|---|---|---|---|
| UniProtKB:Q4V8R0 | InterPro | 176 |
Interactions and Pathways
No data available
Plasmids
No data available