Gene

fbxo7

ID
ZDB-GENE-050913-68
Name
F-box protein 7
Symbol
fbxo7 Nomenclature History
Previous Names
  • si:ch211-286m4.2
  • zgc:114096
Type
protein_coding_gene
Location
Chr: 4 Mapping Details/Browsers
Description
Predicted to enable protein kinase binding activity. Acts upstream of or within musculoskeletal movement. Is expressed in brain; heart; and liver. Human ortholog(s) of this gene implicated in Parkinson's disease and Parkinson's disease 15. Orthologous to human FBXO7 (F-box protein 7).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
3 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
4 figures from Zhao et al., 2012
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With fbxo7 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Parkinson's disease 15 Alliance Parkinson disease 15, autosomal recessive 260300
Associated With fbxo7 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001810 F-box domain
Domain IPR021625 PI31 proteasome regulator, N-terminal
Homologous_superfamily IPR036047 F-box-like domain superfamily
Domain Details Per Protein
Protein Length F-box domain F-box-like domain superfamily PI31 proteasome regulator, N-terminal
UniProtKB:A0A0R4IFW4 485
UniProtKB:Q4V8X6 486
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-fbxo7 polyclonal Mouse
  • IHC
  • WB
Abnova
2
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations