Gene

amh

ID

ZDB-GENE-050706-192

Name

anti-Mullerian hormone

Symbol

amh Nomenclature History

Previous Names

None

Type

protein_coding_gene

Location

Chr: 22 Mapping Details/Browsers

Description

Predicted to have growth factor activity. Involved in negative regulation of androgen secretion and sperm capacitation. Predicted to localize to extracellular region. Human ortholog(s) of this gene implicated in disorders of sexual development; ovarian carcinoma; and persistent Mullerian duct syndrome. Is expressed in female organism; granulosa cell; male organism; and reproductive system. Orthologous to human AMH (anti-Mullerian hormone).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

65 figures from 48 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 17 figures from 3 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With amh Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
persistent Mullerian duct syndrome	Alliance	Persistent Mullerian duct syndrome, type I	261550

Associated With amh Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR001839	Transforming growth factor-beta, C-terminal
Domain	IPR006799	Anti-Mullerian hormone, N-terminal
Family	IPR021203	Muellerian-inhibiting factor
Homologous_superfamily	IPR029034	Cystine-knot cytokine