Gene

aldoca

ID

ZDB-GENE-050706-128

Name

aldolase C, fructose-bisphosphate, a

Symbol

aldoca Nomenclature History

Previous Names

aldocl (1)
wu:fj56h04
zebrin II (1)
zgc:112357

Type

protein_coding_gene

Location

Chr: 15 Mapping Details/Browsers

Description

Predicted to enable fructose-bisphosphate aldolase activity. Predicted to be involved in fructose 1,6-bisphosphate metabolic process and glycolytic process. Predicted to act upstream of or within protein phosphorylation. Predicted to be active in cytosol. Is expressed in brain. Human ortholog(s) of this gene implicated in autoimmune disease of the nervous system. Orthologous to human ALDOC (aldolase, fructose-bisphosphate C).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

10 figures from 6 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With aldoca Human Ortholog

No data available

Associated With aldoca Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Active_site	IPR008271	Serine/threonine-protein kinase, active site
Conserved_site	IPR029768	Fructose-bisphosphate aldolase class-I active site
Domain	IPR000719	Protein kinase domain
Domain	IPR045270	Serine/Threonine Kinase AGC, catalytic domain
Family	IPR000741	Fructose-bisphosphate aldolase, class-I
Homologous_superfamily	IPR011009	Protein kinase-like domain superfamily
Homologous_superfamily	IPR013785	Aldolase-type TIM barrel