Gene

hepacama

ID
ZDB-GENE-050522-198
Name
hepatic and glial cell adhesion molecule a
Symbol
hepacama Nomenclature History
Previous Names
  • Glialcama (1)
  • hepacam
  • zgc:112363
Type
protein_coding_gene
Location
Chr: 15 Mapping Details/Browsers
Description
Located in cell-cell junction. Is expressed in several structures, including brain; digestive system; eye; pleuroperitoneal region; and radial glial cell. Human ortholog(s) of this gene implicated in megalencephalic leukoencephalopathy with subcortical cysts 2A and megalencephalic leukoencephalopathy with subcortical cysts 2B. Orthologous to human HEPACAM (hepatic and glial cell adhesion molecule).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
3 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
3 figures from PĂ©rez-Rius et al., 2019
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With hepacama Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
megalencephalic leukoencephalopathy with subcortical cysts 2A Alliance Megalencephalic leukoencephalopathy with subcortical cysts 2A 613925
megalencephalic leukoencephalopathy with subcortical cysts 2B Alliance Megalencephalic leukoencephalopathy with subcortical cysts 2B, remitting, with or without impaired intellectual development 613926
Associated With hepacama Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR003598 Immunoglobulin subtype 2
Domain IPR003599 Immunoglobulin subtype
Domain IPR007110 Immunoglobulin-like domain
Domain IPR013098 Immunoglobulin I-set
Domain IPR013106 Immunoglobulin V-set domain
Homologous_superfamily IPR013783 Immunoglobulin-like fold
Homologous_superfamily IPR036179 Immunoglobulin-like domain superfamily
Domain Details Per Protein
Protein Length Immunoglobulin I-set Immunoglobulin-like domain Immunoglobulin-like domain superfamily Immunoglobulin-like fold Immunoglobulin subtype Immunoglobulin subtype 2 Immunoglobulin V-set domain
UniProtKB:F8W2R4 451
UniProtKB:Q502A9 422
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-hepacama polyclonal Rabbit
  • IHC
  • WB
2
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations