Gene
abcd4
- ID
- ZDB-GENE-050517-30
- Name
- ATP-binding cassette, sub-family D (ALD), member 4
- Symbol
- abcd4 Nomenclature History
- Previous Names
-
- zgc:153503
- Type
- protein_coding_gene
- Location
- Chr: 24 Mapping Details/Browsers
- Description
- Predicted to have ATP binding activity; ATPase activity; and ATPase-coupled transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to localize to integral component of membrane. Orthologous to human ABCD4 (ATP binding cassette subfamily D member 4).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Choi et al., 2019
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 2 figures from Choi et al., 2019
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Methylmalonic aciduria and homocystinuria, cblJ type | 614857 |
| Human Disease | Fish | Conditions | Citations |
|---|---|---|---|
| vitamin B12 deficiency | abcd4wk1/wk1 | standard conditions | Choi et al., 2019 |
| vitamin B12 deficiency | WT + MO1-abcd4 | standard conditions | Choi et al., 2019 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR017871 | ABC transporter-like, conserved site |
| Domain | IPR003439 | ABC transporter-like, ATP-binding domain |
| Domain | IPR003593 | AAA+ ATPase domain |
| Domain | IPR011527 | ABC transporter type 1, transmembrane domain |
| Homologous_superfamily | IPR027417 | P-loop containing nucleoside triphosphate hydrolase |
| Homologous_superfamily | IPR036640 | ABC transporter type 1, transmembrane domain superfamily |
Domain Details Per Protein
| Protein | Length | AAA+ ATPase domain | ABC transporter-like, ATP-binding domain | ABC transporter-like, conserved site | ABC transporter type 1, transmembrane domain | ABC transporter type 1, transmembrane domain superfamily | P-loop containing nucleoside triphosphate hydrolase |
|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M2B9T8
|
450 | ||||||
|
UniProtKB:F1Q4Y1
|
604 | ||||||
|
UniProtKB:A0A8M9P5Z5
|
590 |
Interactions and Pathways
No data available
Plasmids
No data available