Gene

itga3b

ID

ZDB-GENE-050411-55

Name

integrin, alpha 3b

Symbol

itga3b Nomenclature History

Previous Names

bdf (1)
fyd (1)
itga3 (1)
badfin (1)
frayed
im:7145180 (1)
im:7155971 (1)
unm tz296
unm_tz296

Type

protein_coding_gene

Location

Chr: 12 Mapping Details/Browsers

Description

Acts upstream of or within fin morphogenesis. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be part of integrin complex. Is expressed in several structures, including cardiovascular system; nervous system; periderm; pharyngeal arch; and pronephros. Orthologous to human ITGA3 (integrin subunit alpha 3).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

10 figures from 5 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

IMAGE:7145180 (16 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 9 figures from 5 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With itga3b Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		Epidermolysis bullosa, junctional 7, with interstitial lung disease and nephrotic syndrome	614748

Associated With itga3b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR018184	Integrin alpha chain, C-terminal cytoplasmic region, conserved site
Domain	IPR013649	Integrin alpha-2
Family	IPR000413	Integrin alpha chain
Homologous_superfamily	IPR028994	Integrin alpha, N-terminal
Homologous_superfamily	IPR032695	Integrin domain superfamily
Repeat	IPR013517	FG-GAP repeat
Repeat	IPR013519	Integrin alpha beta-propellor