Gene

cdh6

ID

ZDB-GENE-050320-92

Name

cadherin 6

Symbol

cdh6 Nomenclature History

Previous Names

zgc:103673

Type

protein_coding_gene

Location

Chr: 2 Mapping Details/Browsers

Description

Is predicted to enable cadherin binding activity and calcium ion binding activity. Involved in several processes, including calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules; cell morphogenesis; and cell-cell junction organization. Acts upstream of or within pronephros development and retina morphogenesis in camera-type eye. Predicted to be located in plasma membrane. Predicted to be integral component of membrane. Predicted to be part of catenin complex. Is expressed in several structures, including nervous system; neural crest cell; pronephros; trigeminal placode; and trunk mesenchyme. Orthologous to several human genes including CDH6 (cadherin 6).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

26 figures from 8 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 10 figures from 2 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With cdh6 Human Ortholog

No data available

Associated With cdh6 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR020894	Cadherin conserved site
Domain	IPR000233	Cadherin, cytoplasmic domain
Domain	IPR002126	Cadherin-like
Family	IPR039808	Cadherin
Homologous_superfamily	IPR015919	Cadherin-like superfamily
Homologous_superfamily	IPR027397	Catenin binding domain superfamily