Gene

cdh6

ID
ZDB-GENE-050320-92
Name
cadherin 6
Symbol
cdh6 Nomenclature History
Previous Names
  • zgc:103673
Type
protein_coding_gene
Location
Chr: 2 Mapping Details/Browsers
Description
Is predicted to enable cadherin binding activity and calcium ion binding activity. Involved in several processes, including calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules; cell morphogenesis; and cell-cell junction organization. Acts upstream of or within pronephros development and retina morphogenesis in camera-type eye. Predicted to be located in plasma membrane. Predicted to be integral component of membrane. Predicted to be part of catenin complex. Is expressed in several structures, including nervous system; neural crest cell; pronephros; trigeminal placode; and trunk mesenchyme. Orthologous to several human genes including CDH6 (cadherin 6).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
26 figures from 8 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
10 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With cdh6 Human Ortholog
No data available
Associated With cdh6 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR020894 Cadherin conserved site
Domain IPR000233 Cadherin, cytoplasmic domain
Domain IPR002126 Cadherin-like
Family IPR039808 Cadherin
Homologous_superfamily IPR015919 Cadherin-like superfamily
Homologous_superfamily IPR027397 Catenin binding domain superfamily
Domain Details Per Protein
Protein Length Cadherin Cadherin conserved site Cadherin, cytoplasmic domain Cadherin-like Cadherin-like superfamily Catenin binding domain superfamily
UniProtKB:Q5WN09 794
UniProtKB:Q5BKW2 794
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-cdh6 polyclonal Rabbit
  • IHC
  • WB
Covance
1
Ab2-cdh6 polyclonal Rabbit
1
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations