Gene
illr3
- ID
- ZDB-GENE-050311-4
- Name
- immune-related, lectin-like receptor 3
- Symbol
- illr3 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 19 Mapping Details/Browsers
- Description
- Predicted to enable carbohydrate binding activity and pattern recognition receptor activity. Acts upstream of or within positive regulation of natural killer cell mediated cytotoxicity. Predicted to be active in external side of plasma membrane. Is expressed in blood; kidney; and spleen. Orthologous to several human genes including CLEC6A (C-type lectin domain containing 6A); CLEC4A (C-type lectin domain family 4 member A); and CLEC4C (C-type lectin domain family 4 member C).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from Panagos et al., 2006
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
No data available
No data available
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR001304 | C-type lectin-like |
| Domain | IPR033989 | CD209-like, C-type lectin-like domain |
| Family | IPR050111 | C-type lectin and snaclec domain-containing protein |
| Family | IPR051379 | C-type Lectin Receptor Immune Modulators |
| Homologous_superfamily | IPR016186 | C-type lectin-like/link domain superfamily |
1 - 5 of 6 Show all
Domain Details Per Protein
| Protein | Additional Resources | Length | CD209-like, C-type lectin-like domain | C-type lectin and snaclec domain-containing protein | C-type lectin fold | C-type lectin-like | C-type lectin-like/link domain superfamily | C-type Lectin Receptor Immune Modulators |
|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M9PGK7 | InterPro | 285 | ||||||
| UniProtKB:Q24K32 | InterPro | 274 | ||||||
| UniProtKB:Q24K31 | InterPro | 261 |
1 - 3 of 3
Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | CH211-133N4 | Panagos et al., 2006 | |
| Encodes | cDNA | MGC:195065 | ZFIN Curated Data | |
| Encodes | cDNA | MGC:195066 | ZFIN Curated Data |
1 - 3 of 3
Show
| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_001040039 (1) | 951 nt | ||
| Genomic | GenBank:AL928975 (1) | 174480 nt | ||
| Polypeptide | UniProtKB:A0A8M9PGK7 (1) | 285 aa |
No data available
- Petit, J., Bailey, E.C., Wheeler, R.T., de Oliveira, C.A.F., Forlenza, M., Wiegertjes, G.F. (2019) Studies Into β-Glucan Recognition in Fish Suggests a Key Role for the C-Type Lectin Pathway. Frontiers in immunology. 10:280
- Bayés, À., Collins, M.O., Reig-Viader, R., Gou, G., Goulding, D., Izquierdo, A., Choudhary, J.S., Emes, R.D., Grant, S.G. (2017) Evolution of complexity in the zebrafish synapse proteome. Nature communications. 8:14613
- Panagos, P.G., Dobrinski, K.P., Chen, X., Grant, A.W., Traver, D., Djeu, J.Y., Wei, S., and Yoder, J.A. (2006) Immune-related, lectin-like receptors are differentially expressed in the myeloid and lymphoid lineages of zebrafish. Immunogenetics. 58(1):31-40
- Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G., Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D., Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K., Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F., Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L., Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L., Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S., Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J., Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J., McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S., Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W., Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A., Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S., Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y., Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D., Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M., Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E., Schnerch,A., Schein,J.E., Jones,S.J., and Marra,M.A. (2002) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proceedings of the National Academy of Sciences of the United States of America. 99(26):16899-903
1 - 4 of 4
Show