Gene

illr3

ID

ZDB-GENE-050311-4

Name

immune-related, lectin-like receptor 3

Symbol

illr3 Nomenclature History

Previous Names

illr3a (1)
illr3b (1)

Type

protein_coding_gene

Location

Chr: 19 Mapping Details/Browsers

Description

Predicted to enable carbohydrate binding activity and pattern recognition receptor activity. Acts upstream of or within positive regulation of natural killer cell mediated cytotoxicity. Predicted to be active in external side of plasma membrane. Is expressed in blood; kidney; and spleen. Orthologous to several human genes including CLEC6A (C-type lectin domain containing 6A); CLEC4A (C-type lectin domain family 4 member A); and CLEC4C (C-type lectin domain family 4 member C).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

2 figures from Panagos et al., 2006

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With illr3 Human Ortholog

No data available

Associated With illr3 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR001304	C-type lectin-like
Domain	IPR033989	CD209-like, C-type lectin-like domain
Family	IPR050111	C-type lectin and snaclec domain-containing protein
Family	IPR051379	C-type Lectin Receptor Immune Modulators
Homologous_superfamily	IPR016186	C-type lectin-like/link domain superfamily
Homologous_superfamily	IPR016187	C-type lectin fold