ZFIN is now using GRCz12tu for Genomic Data
Gene
h2ax1
- ID
- ZDB-GENE-041010-42
- Name
- H2A.X variant histone family member 1
- Symbol
- h2ax1 Nomenclature History
- Previous Names
-
- h2afx1
- zgc:101846 (1)
- Type
- protein_coding_gene
- Location
- Chr: 10 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to be a structural constituent of chromatin. Predicted to be involved in defense response to other organism; disruption of plasma membrane integrity in another organism; and heterochromatin formation. Predicted to be located in extracellular space. Predicted to be part of nucleosome. Predicted to be active in nucleus. Orthologous to several human genes including H2AC21 (H2A clustered histone 21).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:101846 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Histone-fold | Histone H2A | Histone H2A conserved site | Histone H2A, C-terminal domain | Histone H2A/H2B/H3 |
|---|---|---|---|---|---|---|---|
| UniProtKB:Q5XJK2 | InterPro | 128 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
h2afx1-201
(1)
|
Ensembl | 909 nt |
Interactions and Pathways
No data available
| Name | Type | Antigen Genes | Isotype | Host Organism | Assay | Source | Citations |
|---|---|---|---|---|---|---|---|
| Ab4-h2afx | monoclonal | IgG | Rabbit |
|
Cell Signaling Technology, Inc.
|
13 |
Plasmids
No data available
- Genome Browsers