Gene

dnaaf11

ID
ZDB-GENE-040827-2
Name
dynein axonemal assembly factor 11
Symbol
dnaaf11 Nomenclature History
Previous Names
  • sea (1)
  • zar (1)
  • zator (1)
  • lrrc6
  • lrrc6l (1)
  • seahorse (1)
  • unm tg238a
Type
protein_coding_gene
Location
Chr: 2 Mapping Details/Browsers
Description
Involved in several processes, including cilium movement involved in cell motility; embryonic morphogenesis; and motile cilium assembly. Localizes to cytoplasm. Human ortholog(s) of this gene implicated in primary ciliary dyskinesia 19. Is expressed in several structures, including floor plate; forerunner cell group; olfactory pit; pronephros; and tail bud. Orthologous to human LRRC6 (leucine rich repeat containing 6).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
6 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
20 figures from 9 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With dnaaf11 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
primary ciliary dyskinesia 19 Alliance Ciliary dyskinesia, primary, 19 614935
Associated With dnaaf11 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Homologous_superfamily IPR032675 Leucine-rich repeat domain superfamily
Repeat IPR001611 Leucine-rich repeat
Domain Details Per Protein
Protein Length Leucine-rich repeat Leucine-rich repeat domain superfamily
UniProtKB:B3DH20 440
UniProtKB:F1Q7C0 440
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-lrrc6 polyclonal IgG Rabbit
  • IHC
  • WB
Covance
2
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations