Gene

lpar2a

ID
ZDB-GENE-040801-97
Name
lysophosphatidic acid receptor 2a
Symbol
lpar2a Nomenclature History
Previous Names
  • zgc:101053 (1)
Type
protein_coding_gene
Location
Chr: 3 Mapping Details/Browsers
Description
Enables lysophosphatidic acid receptor activity. Acts upstream of or within angiogenesis; negative regulation of erythrocyte differentiation; and thrombocyte differentiation. Predicted to be located in cell surface; endosome; and membrane. Predicted to be active in cytoplasm and plasma membrane. Is expressed in axis and yolk syncytial layer. Orthologous to human LPAR2 (lysophosphatidic acid receptor 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Frisca et al., 2016
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
2 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Allele Type Localization Consequence Mutagen Supplier
sa259Allele with one point mutationUnknownPremature StopENU
1 - 1 of 1
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Sequence Targeting Reagents
Targeting Reagent Created Alleles Citations
MO1-lpar2aN/A (4)
1 - 1 of 1
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Human Disease
Associated With lpar2a Human Ortholog
No data available
Associated With lpar2a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR017452 GPCR, rhodopsin-like, 7TM
Family IPR000276 G protein-coupled receptor, rhodopsin-like
Family IPR002277 Lysophosphatidic acid receptor EDG-2
Family IPR004065 Lysophosphatidic acid receptor
1 - 4 of 4
Domain Details Per Protein
Protein Additional Resources Length GPCR, rhodopsin-like, 7TM G protein-coupled receptor, rhodopsin-like Lysophosphatidic acid receptor Lysophosphatidic acid receptor EDG-2
UniProtKB:Q6DC27 InterPro 356
UniProtKB:F1QFF1 InterPro 356
1 - 2 of 2
Transcripts
Genome Browsers
Genome Build: GRCz11Chromosome: 3
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA lpar2a-201 (1) Ensembl 1,471 nt
mRNA lpar2a-202 (1) Ensembl 3,510 nt
1 - 2 of 2
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
No data available
Marker Relationships
Relationship Marker Type Marker Accession Numbers Citations
Contained inBACCH211-280H11ZFIN Curated Data
Contained inBACDKEY-189E16ZFIN Curated Data
EncodescDNAMGC:101053ZFIN Curated Data
1 - 3 of 3
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Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Species Symbol Chromosome Accession # Evidence
HumanLPAR219
Conserved genome location (synteny) (1)
Amino acid sequence comparison (2)
MouseLpar28
Conserved genome location (synteny) (1)
Amino acid sequence comparison (2)
Citations