Gene

hdac3

ID
ZDB-GENE-040426-847
Name
histone deacetylase 3
Symbol
hdac3 Nomenclature History
Previous Names
  • zgc:55927 (1)
Type
protein_coding_gene
Location
Chr: 14 Mapping Details/Browsers
Description
Predicted to have chromatin binding activity; histone deacetylase activity; and transcription corepressor activity. Involved in several processes, including angiogenesis; liver development; and posterior lateral line development. Predicted to localize to cytoplasm; histone deacetylase complex; and transcriptional repressor complex. Human ortholog(s) of this gene implicated in lung non-small cell carcinoma. Is expressed in several structures, including axial blood vessel; blood vessel; digestive system; otic vesicle; and sensory system. Orthologous to human HDAC3 (histone deacetylase 3).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
14 figures from 7 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
15 figures from 5 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With hdac3 Human Ortholog
No data available
Associated With hdac3 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR023801 Histone deacetylase domain
Family IPR000286 Histone deacetylase family
Family IPR003084 Histone deacetylase
Homologous_superfamily IPR023696 Ureohydrolase domain superfamily
Homologous_superfamily IPR037138 Histone deacetylase domain superfamily
Domain Details Per Protein
Protein Length Histone deacetylase Histone deacetylase domain Histone deacetylase domain superfamily Histone deacetylase family Ureohydrolase domain superfamily
UniProtKB:A0A0R4IPZ3 75
UniProtKB:Q803C3 428
UniProtKB:F1RCG9 428
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations