Gene

ptp4a3a

ID

ZDB-GENE-040426-2220

Name

protein tyrosine phosphatase 4A3a

Symbol

ptp4a3a Nomenclature History

Previous Names

PRL-3 (1)
ptp4a3
wu:fc54b05
wu:fv52d11
zgc:77109

Type

protein_coding_gene

Location

Chr: 19 Mapping Details/Browsers

Description

Predicted to enable protein tyrosine phosphatase activity. Predicted to act upstream of or within protein dephosphorylation. Predicted to be active in cytoplasm and nucleus. Is expressed in several structures, including alar plate midbrain region; cephalic musculature; digestive system; germ ring; and nervous system. Orthologous to human PTP4A3 (protein tyrosine phosphatase 4A3).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

8 figures from 3 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

MGC:77109 (9 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With ptp4a3a Human Ortholog

No data available

Associated With ptp4a3a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000242	Tyrosine-specific protein phosphatase, PTPase domain
Domain	IPR000340	Dual specificity phosphatase, catalytic domain
Domain	IPR000387	Tyrosine-specific protein phosphatases domain
Domain	IPR003595	Protein-tyrosine phosphatase, catalytic
Domain	IPR020422	Dual specificity protein phosphatase domain
Homologous_superfamily	IPR029021	Protein-tyrosine phosphatase-like

Domain Details Per Protein

Protein	Length	Dual specificity phosphatase, catalytic domain	Dual specificity protein phosphatase domain	Protein-tyrosine phosphatase, catalytic	Protein-tyrosine phosphatase-like	Tyrosine-specific protein phosphatase, PTPase domain	Tyrosine-specific protein phosphatases domain
UniProtKB:F8W486 InterPro	61
UniProtKB:Q6NX92 InterPro	173
UniProtKB:F8W245 InterPro	74
UniProtKB:F8W630 InterPro	120
UniProtKB:A7MCI2 InterPro	173

Transcripts

Genome Browsers

Type	Name	Length (nt)	Analysis
mRNA	ptp4a3-201 (1) Ensembl	1887 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	ptp4a3-202 (1) Ensembl	699 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	ptp4a3-203 (1) Ensembl	639 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	ptp4a3-204 (1) Ensembl	830 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
ncRNA	ptp4a3-002 (1) Ensembl	819 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
ncRNA	ptp4a3-006 (1) Ensembl	776 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations