Gene

insm1a

ID
ZDB-GENE-040426-1810
Name
insulinoma-associated 1a
Symbol
insm1a Nomenclature History
Previous Names
  • zgc:77257
Type
protein_coding_gene
Location
Chr: 20 Mapping Details/Browsers
Description
Enables DNA-binding transcription factor activity, RNA polymerase II-specific and sequence-specific DNA binding activity. Involved in negative regulation of transcription by RNA polymerase II. Acts upstream of or within several processes, including sensory epithelium regeneration; sensory system development; and spinal cord motor neuron differentiation. Predicted to be part of transcription repressor complex. Predicted to be active in nucleus. Is expressed in several structures, including nervous system; optic cup; pancreas primordium; presumptive telencephalon; and trigeminal placode. Orthologous to human INSM1 (INSM transcriptional repressor 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
23 figures from 13 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
20 figures from 3 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With insm1a Human Ortholog
No data available
Associated With insm1a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR013087 Zinc finger C2H2-type
Family IPR042972 Insulinoma-associated protein 1/2
Homologous_superfamily IPR036236 Zinc finger C2H2 superfamily
Domain Details Per Protein
Protein Length Insulinoma-associated protein 1/2 Zinc finger C2H2 superfamily Zinc finger C2H2-type
UniProtKB:F8W3Z6 373
UniProtKB:Q6P0F9 383
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations