ZFIN is now using GRCz12tu for Genomic Data
Gene
ndrg1b
- ID
- ZDB-GENE-040426-1648
- Name
- N-myc downstream regulated 1b
- Symbol
- ndrg1b Nomenclature History
- Previous Names
-
- ndrg1l
- zgc:73047
- Type
- protein_coding_gene
- Location
- Chr: 16 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Acts upstream of or within regulation of T cell differentiation and thymus development. Predicted to be active in cytoplasm. Is expressed in epiphysis; optic vesicle; pro-T cell; retina; and thymus. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease type 4D. Orthologous to human NDRG1 (N-myc downstream regulated 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 12 figures from 7 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:73047 (8 images)
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Li et al., 2016
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Charcot-Marie-Tooth disease type 4D | Alliance | Charcot-Marie-Tooth disease, type 4D | 601455 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Alpha/Beta hydrolase fold | NDRG |
|---|---|---|---|---|
| UniProtKB:F1R8D1 | InterPro | 359 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
ndrg1b-201
(1)
|
Ensembl | 1,778 nt |
Interactions and Pathways
No data available
| Name | Type | Antigen Genes | Isotype | Host Organism | Assay | Source | Citations |
|---|---|---|---|---|---|---|---|
| Ab1-ndrg1b | Mouse |
|
1 |
Plasmids
No data available
- Genome Browsers