Gene
prkcbb
- ID
- ZDB-GENE-040426-1178
- Name
- protein kinase C, beta b
- Symbol
- prkcbb Nomenclature History
- Previous Names
-
- prkcb1
- zgc:63591 (1)
- Type
- protein_coding_gene
- Location
- Chr: 3 Mapping Details/Browsers
- Description
- Predicted to enable several functions, including nuclear androgen receptor binding activity; protein serine/threonine kinase activity; and transcription coactivator activity. Acts upstream of or within blood coagulation and embryonic hemopoiesis. Predicted to be located in nucleus. Is expressed in brain; retinal neural layer; and somite border. Human ortholog(s) of this gene implicated in dilated cardiomyopathy and lung non-small cell carcinoma. Orthologous to human PRKCB (protein kinase C beta).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 8 figures from 8 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | AGC-kinase, C-terminal | C1-like domain superfamily | C2 domain | C2 domain superfamily | Classical protein kinase C beta, catalytic domain | Diacylglycerol/phorbol-ester binding | Protein kinase, ATP binding site | Protein kinase C, alpha/beta/gamma types | Protein kinase C-like, phorbol ester/diacylglycerol-binding domain | Protein kinase, C-terminal | Protein kinase domain | Protein kinase-like domain superfamily | Serine/threonine-protein kinase, active site |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A2R8QMW2 | InterPro | 670 | |||||||||||||
| UniProtKB:Q7SY24 | InterPro | 670 |
1 - 2 of 2
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
prkcbb-201
(1)
|
Ensembl | 4,340 nt | ||
| mRNA |
prkcbb-202
(1)
|
Ensembl | 4,732 nt |
1 - 2 of 2
Interactions and Pathways
No data available
| Name | Type | Antigen Genes | Isotype | Host Organism | Assay | Source | Citations |
|---|---|---|---|---|---|---|---|
| Ab1-prkcb1 | monoclonal | IgG1 | Mouse |
|
Santa Cruz Biotechnology, Inc.
|
5 | |
| Ab2-prkcb1 | polyclonal | IgG | Rabbit |
|
Santa Cruz Biotechnology, Inc.
|
2 |
1 - 2 of 2
Plasmids
No data available