Gene

nr1i2

ID
ZDB-GENE-030903-3
Name
nuclear receptor subfamily 1, group I, member 2
Symbol
nr1i2 Nomenclature History
Previous Names
  • PXR (1)
Type
protein_coding_gene
Location
Chr: 9 Mapping Details/Browsers
Description
Exhibits nuclear receptor activity and steroid hormone receptor activity. Involved in regulation of transcription, DNA-templated; response to toxic substance; and transcription by RNA polymerase II. Predicted to localize to RNA polymerase II transcription factor complex. Is expressed in several structures, including adenohypophyseal placode; brain; heart; liver; and pleuroperitoneal region. Orthologous to human NR1I2 (nuclear receptor subfamily 1 group I member 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
21 figures from 9 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Hu et al., 2019
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With nr1i2 Human Ortholog
No data available
Associated With nr1i2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000536 Nuclear hormone receptor, ligand-binding domain
Domain IPR001628 Zinc finger, nuclear hormone receptor-type
Family IPR001723 Nuclear hormone receptor
Homologous_superfamily IPR013088 Zinc finger, NHR/GATA-type
Homologous_superfamily IPR035500 Nuclear hormone receptor-like domain superfamily
Domain Details Per Protein
Protein Length Nuclear hormone receptor Nuclear hormone receptor, ligand-binding domain Nuclear hormone receptor-like domain superfamily Zinc finger, NHR/GATA-type Zinc finger, nuclear hormone receptor-type
UniProtKB:A0A3G3LK92 321
UniProtKB:Q8QGH6 322
UniProtKB:Q8JIZ9 329
UniProtKB:A0A3G3LJZ1 431
UniProtKB:A0A3G3LK54 430
UniProtKB:A0A3G3LK86 431
UniProtKB:B0V1H8 430
UniProtKB:A5WYG8 430
UniProtKB:A0A3G3LKB0 430
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations