Gene

birc5b

ID
ZDB-GENE-030826-2
Name
baculoviral IAP repeat containing 5b
Symbol
birc5b Nomenclature History
Previous Names
  • survivin 2 (1)
Type
protein_coding_gene
Location
Chr: 23 Mapping Details/Browsers
Description
Is predicted to enable cysteine-type endopeptidase inhibitor activity involved in apoptotic process. Involved in regulation of cell cycle. Acts upstream of or within several processes, including circulatory system development; nuclear division; and regulation of apoptotic process. Is expressed in several structures, including axial blood vessel; caudal vein plexus; intermediate cell mass of mesoderm; nervous system; and unfertilized egg. Human ortholog(s) of this gene implicated in prostate cancer and transitional cell carcinoma. Orthologous to human BIRC5 (baculoviral IAP repeat containing 5) and BIRC7 (baculoviral IAP repeat containing 7).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
9 figures from 7 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
16 figures from 4 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With birc5b Human Ortholog
No data available
Associated With birc5b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Repeat IPR001370 BIR repeat
Domain Details Per Protein
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab2-birc5 monoclonal IgG Rabbit
  • IHC
Cell Signaling Technology, Inc.
3
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations