Gene

rtn4b

ID

ZDB-GENE-030710-2

Name

reticulon 4b

Symbol

rtn4b Nomenclature History

Previous Names

rtn6

Type

protein_coding_gene

Location

Chr: 13 Mapping Details/Browsers

Description

Acts upstream of or within embryonic viscerocranium morphogenesis; nervous system development; and sensory system development. Predicted to be located in endoplasmic reticulum membrane. Is expressed in several structures, including gill; heart; nervous system; notochord; and otic vesicle. Orthologous to human RTN4 (reticulon 4).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

7 figures from 3 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 4 figures from Pinzón-Olejua et al., 2014
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With rtn4b Human Ortholog

No data available

Associated With rtn4b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR003388	Reticulon
Family	IPR003882	Pistil-specific extensin-like protein

Domain Details Per Protein

Protein	Length	Pistil-specific extensin-like protein	Reticulon
UniProtKB:Q4G5U5 InterPro	655
UniProtKB:Q4G5T8 InterPro	860
UniProtKB:Q4G5U3 InterPro	749
UniProtKB:A0A0R4IF59 InterPro	523
UniProtKB:A0A0R4INK8 InterPro	861
UniProtKB:Q4G5U1 InterPro	815
UniProtKB:Q4G5U4 InterPro	753
UniProtKB:A0A0R4ICW0 InterPro	746
UniProtKB:Q4G5U8 InterPro	780
UniProtKB:Q4G5U9 InterPro	802
UniProtKB:Q4G5T9 InterPro	522
UniProtKB:A0A0R4IL48 InterPro	876
UniProtKB:A0A0R4ISY7 InterPro	656
UniProtKB:Q4G5U6 InterPro	641
UniProtKB:Q4G5V0 InterPro	875
UniProtKB:Q4G5U2 InterPro	685
UniProtKB:Q4G5U0 InterPro	680
UniProtKB:Q4G5U7 InterPro	745

Transcripts

Genome Browsers

NCBI

No data available

Interactions and Pathways

No data available

Antibodies

Name	Type	Antigen Genes	Isotype	Host Organism	Assay	Source	Citations
Ab1-rtn4b	polyclonal	rtn4b		Rabbit	IHC OTHR WB		3

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations